Thursday, October 30, 2014

US: According to AP, US Healthcare System Ill-Prepared for Ebola

According to he excellent reporting of The Associated Press, the US health care apparatus is so unprepared and short on resources to deal with the deadly Ebola virus that even small clusters of cases could overwhelm major parts of the system, according to an AP review of readiness at hospitals and other components of the emergency medical network.

To assess America's ability to deal with a major outbreak, the AP examined multiple indicators of readiness: training, manpower, funding, emergency room shortcomings, supplies, infection control and protection for health care workers. 

AP reporters also interviewed dozens of top experts in those fields. Experts broadly agree that a widespread outbreak across the country is extremely unlikely, but they also concur that it is impossible to predict with certainty, since previous Ebola epidemics have been confined to remote areas of Africa. 

Ebola is not the only possible danger that causes concern; experts say other deadly infectious diseases--ranging from airborne viruses such as SARS, to an unforeseen new strain of the flu, to more exotic plagues like Lassa fever--could potentially crash the health care system.

Following the death of a patient with Ebola in a Texas hospital and the subsequent infection of two of his nurses, medical officials and politicians are scurrying to fix preparedness shortcomings. Yet, remedies cannot be implemented overnight. Fixes will be very expensive.
Dr. Jeffrey S. Duchin, chairman of the Public Health Committee of the Infectious Diseases Society of America and a professor of medicine at the University of Washington, said it will take time to ramp up readiness, including ordering the right protective equipment and training workers to use it. "Not every facility is going to be able to obtain the same level of readiness," he said.
"The place I worry is: Are most small hospitals adequately prepared?" said Dr. Ashish Jha, a Harvard University specialist in health care quality and safety. "It clearly depends on the hospital."
He said better staff training is the most important element of preparation for any US Ebola outbreak. He believes a small group of personnel at each hospital needs to know the best procedures, because sick people are likely to appear first at medium-size or small medical centers, which are much more common than large ones.
Without any stress caused by Ebola cases, the emergency care system in the US is already overextended. In its 2014 national report card, the American College of Emergency Physicians gives the country a D-plus grade in emergency care, asserting the system is in "near-crisis," overwhelmed even by the usual demands of care.
Patients spend an average of 4.5 hours in emergency rooms of US hospitals before being admitted. The data also show that 2% of patients leave before even being seen.
In a US Centers for Disease Control and Prevention study on hospital preparedness for emergency response in 2008, the latest data available, at least a third of hospitals had to divert ambulances because their emergency rooms were at capacity.
"Even though there have been only a couple cases, many health systems are already overwhelmed," said Dr. Kenrad Nelson, a professor at Johns Hopkins Bloomberg School of Public Health and former president of the American Epidemiological Society, referring to new federal procedures for screening, tracking and treating the disease and people who are exposed. He added that if a major flu outbreak also occurred, "it would be really tough."
"We're really going to have to step up our game if we are going to deal with hemorrhagic fevers in this country," said Lawrence Gostin, a global health law expert and professor at Georgetown University.
One federal study on emergency room visits indicated that at least 4% of visits involved patients with fever--a common symptom of Ebola. Combining fevers with stomach pain, headaches and coughs, about a fifth of emergency visits involve symptoms often seen in Ebola patients.
A doctor who had recently treated Ebola patients in West Africa came into Bellevue Hospital in New York City last week with a fever and gastrointestinal symptoms. In announcing the man had been placed in isolation, officials pointed out how his symptoms also could be consistent with salmonella, malaria or the stomach flu. Last Thursday, the doctor tested positive for Ebola.
National surveys have repeatedly found that while most health care providers are willing to care for people with dangerous diseases like Ebola, they generally feel unprepared to do so.
This summer, health care research group Black Book Rankings sought opinions from hospital administrators, doctors and nurses at all US hospitals and health care facilities about infection control, emergency planning and disaster readiness regarding Ebola. Nearly 1,000 personnel at 389 facilities, including 282 hospitals, participated.
Personnel at almost all hospitals in the Black Book survey said their facilities were not capable of quarantining large numbers of people possibly exposed to Ebola.
Nearly three-quarters of emergency doctors and four in five infection specialists at large hospitals felt their facilities were not adequately prepared to deal with Ebola patients.
Hospital administrators and medical staff had widely divergent perspectives on their facilities' ability to treat the disease. Among medical staff at big hospitals, nearly all who participated in the survey believed their hospitals were not adequately staffed and trained for Ebola patients. 
Among emergency nurses, nearly all worried about the impact of emergency department crowding on the ability to deal with Ebola patients; just more than half of administrative and financial managers felt that way.
Other striking results: Personnel at only 1% of surveyed acute care hospitals said they can handle more than ten Ebola patients at once. That was true at just about one-quarter of academic medical centers.
A demonstrated weakness of US hospitals in controlling other hospital-acquired infections also suggests a soft spot in Ebola readiness. 

In 2011, the most recent year of data, about 75,000 hospital patients with health care-associated infections died during their hospitalizations, according to a national CDC survey published this year. Such infections are considered to be a proxy to US hospital readiness to contain Ebola.
Added Douglas Brown, managing partner at Black Book: "We got a lot of feedback that community hospitals aren't the place for Ebola patients to visit."

COMMENT: During the course of my 70 years of living, I have yet to witness US federal agencies functioning at such cross-purposes and at assumed levels of incompetency. Perhaps we are witnessing the rise and fall of a once great nation.

CDC estimates from 2008, the most recent available national figures, put the average number of protective suits with powered air-purifying respirators per hospital at 10. The average hospital had six mechanical ventilators, which could be needed for Ebola patients with breathing problems.
A recent nationwide survey of state public health departments suggests not all are ready to ramp up quickly. The 2013 National Health Security Preparedness Index, carried out by CDC in partnership with the Association for State and Territorial Health Officials, ranks state health departments on a scale of 1 to 10 on numerous emergency measures. In the category of "surge management," the average score was 5.8.
Dr. Amesh Adalja, a member of the Public Health Committee of the Infectious Disease Society of America, says some emergency departments are so consumed by the typical number of patients that a surge of any kind can overwhelm them. With an Ebola outbreak, he said, "they're not just getting a surge of patients, they're getting a surge of patients with special needs."
The AP review found evidence that the federal emergency public health network, which is designed to step in to prevent shortages of medicine and medical supplies while local response capacity ramps up, is failing to perform as planned.
Since 2007, Ebola has been identified as a potential threat requiring priority attention under the Public Health Emergency Medical Countermeasures Enterprise, which coordinates the development, stockpiling and dispensing of drugs during a massive disease outbreak or to protect against chemical, biological, radiological or nuclear agents.
The National Institute of Allergy and Infectious Diseases has spent nearly $500 million on Ebola research since 2003. At least another $269 million has been spent on Ebola research under a Defense Department chemical and biological defense program. Some of that funding was spent on vaccine research and better diagnostic testing.
In October 2011, the GAO reported that an anticipated budget for drug acquisitions still had not been produced. Without clear guidance about government funding, pharmaceutical and other medical companies might not want to invest millions of dollars to develop vaccines that are less lucrative than other drugs they could make, the report underscored.
In fact, the feds' Biomedical Advanced Research and Development Authority did not fund its first investment in an experimental Ebola treatment until this year because that program only supports potential treatments in a later phase of development. 

The US Department of Health and Human Services said a relatively modest $25 million has gone to study ZMapp, an experimental drug in short supply that has been provided to numerous infected Ebola patients.
Given that there is no Ebola vaccine, the government does not have a stockpile of disease-specific drugs on hand, as it has had for pandemic flu.
As of last week, there were no national emergency stockpiles of the waterproof gowns, surgical hoods, full face shields, boot covers or other gear that the CDC recommends for treating Ebola patients. 

CDC's $6.2 billion Strategic National Stockpile had just a small quantity of older model gowns on hand, since most were sent to the states during the 2009 swine flu pandemic and had not been replenished, said Greg Burel, director of the agency's stockpile division. 
If the US sustains a major Ebola outbreak, the mechanism for confirming individual patient test results also could be quickly overwhelmed, though the testing situation suddenly is improving. 

For years, spending on diagnostic research has lagged under the National Institute of Allergy and Infectious Diseases and a US Defense Department chemical and biological defense program. The CDC noted in August that the agency and the military had "the only US laboratories capable of conducting diagnostic testing to confirm that a patient has Ebola and not some other illness." 
Shortcomings in training and preparedness for health care workers are pronounced, and chronic.
More than half of working registered nurses reported they neither received nor provided emergency training during the previous year, according to a study HHS published in 2010 using 2008 data. Of those registered nurses who did receive or provide emergency training, 44% felt somewhat or not at all prepared.
Regarding epidemic response planning, a third of hospitals had no plans for alternate care areas with beds, staffing and equipment, according to a study published in 2011 by CDC's National Center for Health Statistics, again based on 2008 data. 

Only half had priority-setting plans to get the most use from a limited supply of ventilators. More than a third had no plans for on-site, large-capacity morgues and a third had no plans for staff absences as a result of the personal or family impact of any epidemic.
Gostin, the global health law expert from Georgetown, thinks the contamination of two nurses at Texas Health Presbyterian hospital in Dallas, where the first person diagnosed with Ebola in the US died, "was not an anomaly." He said the US may have the most advanced health care system in the world, but the system is very fragmented because "there's no uniform national quality control."
According to the Black Book report, only a quarter of academic medical centers had epidemic or biological warfare drills in the previous year, but just 4% of medium-size hospitals ran such exercises, and no small hospitals did.
Kristi L. Koenig, director of the Center for Disaster Medical Sciences at the University of California-Irvine, said every hospital needs to have some basic level of preparation, in order to manage the initial treatment. But she suggested the best solution is to increase the number of specialized biocontainment centers.
Dr. Patrick Smith, who leads the Biocontainment Unit at the University of Nebraska Medical Center, said that staffers in the typical hospital isolation ward have had little or no practice in putting on and taking off safety gear, or following other procedures for handling Ebola patients. 
In the Black Book Ebola readiness survey released in August, some medical staff said they believed they would stay away from work to shun Ebola patients admitted to their hospitals.
Among isolation care doctors and nurses, 14% said they'd call in sick, and one in four critical care and emergency staff said the same. Among the isolation care staff, 17% said they wouldn't work near Ebola patients; half of critical care and emergency staff said the same.
But Dr. Nelson of Johns Hopkins pointed to the "huge problem" in Africa, where health care workers have walked off the job in large numbers….I think that could be a problem in the United States, because a lot of the population is really terrified," he said.

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